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Mojca Jensterle, from the University Medical Center Ljubljana, explains: "The combined action of both pharmacotherapies, GLP-1 and metformin, may be more effective than the individual action of each drug for the treatment of the metabolic and reproductive disturbances linked to PCOS and may even improve metabolic outcomes in women who previously exhibited deficient responses to metformin." Mojca Jensterle, Department of Endocrinology, University Medical Center Ljubljana Interestingly, metformin has the ability to enhance the bodys natural GLP-1 levels, which might allow for lower doses of GLP-1 receptor agonists without sacrificing results

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Adjust Your Injection Timing Some people find that taking their GLP-1 injection at night instead of in the morning helps reduce nausea during the day